منابع مشابه
Single Prostatic Cancer Foci on Prostate Biopsy
As a consequence of the detection of prostate cancer at an earlier stage, urologists increasingly must deal with the finding of a single small focus of prostatic cancer identified in prostate needle biopsies. Detection of these small cancer foci raises both diagnostic and clinical problems. For pathologists, it may be challenging to make a definite diagnosis of prostate cancer, avoiding confusi...
متن کاملOptimization of prostatic biopsy: a prospective randomized trial comparing the sextant biopsy with a 10-core biopsy. Impact of prostatic region of sampling.
OBJECTIVE New prostatic biopsy protocols suggest to increase the core numbers to enhance detection. Additional cores are usually sampled from the lateral part of the p-zone. We direct the sextant biopsy to the most lateral part of the p-zone, therefore we investigated if there is a gain by adding 4 median biopsy cores. MATERIAL AND METHODS The prospective randomized trial (n = 200) compared o...
متن کاملEndothelin-1 expression in prostate needle biopsy specimens correlated with aggressiveness of prostatic cancer
Background & Objective: As the prostate adenocarcinoma is one of the most common malignant tumors in males, looking for a marker to effectively predict aggressiveness and metastatic potential in an apparently localized cancer in initial needle biopsy specimens can help the clinicians to make more appropriate decision for treatment, planning, and choosing appropriate ta...
متن کاملSerum testosterone as a biomarker for second prostatic biopsy in men with negative first biopsy for prostatic cancer and PSA>4ng/mL, or with PIN biopsy result
INTRODUCTION Data from animal, clinical and prevention studies support the role of androgens in prostate cancer growth, proliferation and progression. Results of serum based epidemiologic studies in humans, however, have been inconclusive. The present study aims to define whether serum testosterone can be used as a predictor of a posi¬tive second biopsy in males considered for re-biopsy. MATE...
متن کاملFactors predicting prostatic biopsy Gleason sum under grading.
PURPOSE We determined clinical factors affecting the under grading of biopsy Gleason sum compared with prostatectomy pathology and developed a model predicting the probability of under grading. MATERIALS AND METHODS We analyzed a cohort of 1,701 patients treated for prostate cancer at our institution between 1988 and 2007 with complete biopsy and pathological data available. Patients with a b...
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ژورنال
عنوان ژورنال: BMJ
سال: 1980
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.281.6244.872-b